Zarko Stanacev experienced years of mysterious, debilitating symptoms. He applied to the NIH's Undiagnosed Diseases Network (UDN) and had his genome sequenced and interpreted by a team including Dr. William Gahl of the US National Institutes of Health. They discovered a mutation in the NLRP3 gene, which causes abnormal inflammation throughout the body. After just one treatment with a medication intended to reduce this inflammation, Zarko's symptoms improved.

The video was produced by 42 Degrees North Media on behalf of the National Human Genome Research Institute.

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