Although all living things have much in common, different organisms can have very different reactions to the same organic chemicals. This means that it is very important for organic chemists to be able to purify chemicals and separate the desired products from unnecessary side-product reactions. In this episode of Crash Course Organic Chemistry, we head into the lab to learn one of the ways we can separate chemicals in a mixture: chromatography!

Episode sources:
Mahdi, J.G. (2010). Medicinal potential of willow: a chemical perspective of the discovery of aspirin. Journal of the Saudi Chemical Society, 14(3), 317-322.
Dempsey, DA, Klessig, DF How does salicylic acid, a multifaceted plant hormone, fight disease in plants and are similar mechanisms used in humans?. BMC Biol 15, 23 (2017). https://doi.org/10.1186/s12915-017-0364-8
However, WC, Kahn, M. and Mitra, A. (1978). Rapid chromatographic technique for preparative separations with moderate resolution. The Journal of Organic Chemistry, 43(14), 2923-2925.
Pastre, JC and Duarte Correia, CR (2006). Efficient Heck arylations of cyclic and acyclic acrylate derivatives using arenediazonium tetrafluoroborates. A new synthesis of the antidepressant ()-Paroxetine. Organic Letters, 8(8), 1657-1660.

Series sources:
Brown, WH, Iverson, BL, Ansyln, EV, Foote, C., Organic Chemistry; 8th ed.; Cengage Learning, Boston, 2018.
Bruice, P.Y., Organic Chemistry, 7th ed.; Pearson Education, Inc., USA, 2014.
Clayden, J., Greeves, N., Warren., S., Organic Chemistry, 2nd ed.; Oxford University Press, New York, 2012.
Jones Jr., M.; Fleming, SA, Organic Chemistry, 5th ed.; WW Norton & Company, New York, 2014.
Klein., D., Organic Chemistry; 1st ed.; John Wiley & Sons, United States, 2012.
Louden M., Organic Chemistry; 5th ed.; Roberts and Company Publishers, Colorado, 2009.
McMurry, J., Organic Chemistry, 9th ed.; Cengage Learning, Boston, 2016.
Smith, JG, Organic Chemistry; 6th ed.; McGraw-Hill Education, New York, 2020.
Wade., LG, Organic Chemistry; 8th ed.; Pearson Education, Inc., USA, 2013.

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